Public Release: 

Antibody neutralizes Zika virus in mice

Proceedings of the National Academy of Sciences

A study of Zika virus in murine models found that mice injected with a single dose of ZIKV-195, a neutralizing monoclonal antibody, 5 days after viral exposure were protected against the virus; the findings suggest that ZIKV-195 cross-links viral envelope proteins that are critical for viral and cellular membrane fusion, which in turn neutralizes Zika virus, according to the authors.

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Article #18-15432: "Structural basis of a potent human monoclonal antibody against Zika virus targeting a quaternary epitope," by Feng Long et al.

MEDIA CONTACT: Michael G. Rossmann, Purdue University, West Lafayette, IN; tel: 765-494-4911, 765-409-0238, 765-494-4909; email: mr@purdue.edu

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