A murine study of septic shock found that compared with mice fed a high-fiber, low-fat diet, mice fed a Western diet, which is characterized as being low in fiber and high in fat and sucrose, exhibited increased chronic low-level inflammation, more severe sepsis pathology, and higher mortality rates; the findings suggest that chronic exposure to the Western diet might affect the immune system and outcome of septic shock.
Article #18-14273: "Western diet regulates immune status and the response to LPS-driven sepsis independent of diet-associated microbiome," by Brooke A. Napier et al.
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