Public Release: 

Hurricane Maria had a significant impact on HIV care outcomes

Columbia University's Mailman School of Public Health

Hurricane Maria in San Juan, Puerto Rico had a significant impact on HIV outcomes among people living with HIV and a history of substance use, particularly increased viral load and decreased CD4 counts, according to early data just released by Columbia University Mailman School of Public Health, University of Puerto Rico, University of Miami, Puerto Rico Department of Health, Iniciativa Comunitaria de Investigación at CROI 2019, at the annual Conference on Retroviruses and Opportunistic Infections, held this year in Seattle. The average viral load following the Hurricane was significantly (11%) higher compared to the pre-Hurricane Maria viral load assessment.

In 2017, Hurricane Maria caused devastation to the island of Puerto Rico and its residents but until now, the health impacts of this storm on vulnerable populations, including people living with HIV were unknown. The study, conducted in San Juan, also found that HIV care outcomes were related to the participants' pre-hurricane viral suppression status.

Through a computer-assisted personal interview, the researchers studied a cohort of people living with HIV and a history of substance use from the San Juan Metropolitan Area using a social and behavioral assessment. They also collected blood samples to measure CD4 and viral load at the study launch and at 6-month follow-up visits, including time points before and after the Hurricane.

Indicators such as homelessness, drug and alcohol use in the past 6 months, depression, physical abuse/interpersonal violence, access to care, and social support, among others, were also assessed.

Viral suppression decreased from 71 percent to 65 percent across the sample as a result of the impacts of Hurricane Maria, and access to care was reduced by over 22 percent. Study participants who were not virally suppressed pre-Hurricane Maria had significantly less access to care and lower medication adherence, but made a greater number of hospital/clinic/outpatient visits post-Hurricane Maria compared to pre-Hurricane Maria.

"The impact of Hurricane Maria on people living with HIV with a history of substance use in San Juan was mixed," observed Diana Hernandez, PhD, first author and Assistant Professor of Sociomedical Sciences at Columbia University's Mailman School of Public Health. "But from our results it is clear to see the benefits of conducting further research that will help us understand divergent paths following natural disasters for vulnerable populations."


Co-authors include Lisa R. Metsch, Pedro C. Castellón, Sandra Miranda de León, Glenda O. Davila-Torres, Yue Pan, Allan E. Rodriguez, Iveth G. Yanez, Mariela Maisonet Alejandro, Wilmarie L. Calderón Alicea, Gabriel Cardenas, Héctor Meléndez, Lauren Gooden, Daniel J. Feaster and Jorge Santana-Bagur. Weill Cornell Medical College (led by Bruce Schackman, PhD) is also collaborating on this study.

The study was supported by the National Institute on Drug Abuse (R01DA035280). The study principal investigators are Lisa R. Metsch, PhD (Columbia University), Jorge Santana-Bagur, MD (University of Puerto Rico) and Sandra Miranda de Leon, MPH (Puerto Rico Department of Health).

Columbia University Mailman School of Public Health

Founded in 1922, the Columbia University Mailman School of Public Health pursues an agenda of research, education, and service to address the critical and complex public health issues affecting New Yorkers, the nation and the world. The Columbia Mailman School is the third largest recipient of NIH grants among schools of public health. Its over 450 multi-disciplinary faculty members work in more than 100 countries around the world, addressing such issues as preventing infectious and chronic diseases, environmental health, maternal and child health, health policy, climate change & health, and public health preparedness. It is a leader in public health education with over 1,300 graduate students from more than 40 nations pursuing a variety of master's and doctoral degree programs. The Columbia Mailman School is also home to numerous world-renowned research centers, including ICAP and the Center for Infection and Immunity. For more information, please visit

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