While the number of babies who die from sudden infant death syndrome (SIDS) has been on the decline, a study by researchers at Florida Atlantic University's Schmidt College of Medicine and collaborators shows that infant deaths from accidental suffocation and strangulation in bed have more than tripled between 1999 and 2016 in the United States with increases in racial inequalities.
Findings from the study, published in the Maternal and Child Health Journal, reveal similar risk factor profiles for non-Hispanic black infants and non-Hispanic white infants, though in every instance, non-Hispanic black rates were higher than those for non-Hispanic whites. Data from the study generate new theories about the occurrence of infant deaths in bed and racial inequalities by identifying factors that may be associated with increased as well as decreased risks.
For the study, researchers examined race, ethnicity, and sex-specific infant mortality rates by state. Findings reveal that infant mortality rates increased from 10.4 per 100,000 live births in 1999 to 45.8 per 100,000 live births in 2016 among non-Hispanic black female infants; from 15.4 to 53.8 for non-Hispanic black male infants; from 5.9 to 15.8 for non-Hispanic white female infants, and from 6.5 to 25.9 for non-Hispanic white male infants (1999 to 2016). All increases over time were statistically significant.
Between 2007 and 2016, 83 percent of all U.S. deaths in bed among non-Hispanic black and non-Hispanic white infants occurred to mothers who lived in the Midwest and the South at the time of delivery.
The highest mortality rate occurred among non-Hispanic blacks in Michigan (126.4 per 100,000 live births) compared to 11.8 per 100,000 live births for non-Hispanic blacks in California. The highest corresponding rate for non-Hispanic whites occurred in Mississippi (45 per 100,000 live births) and the lowest rate occurred in California (6.5 per 100,000 live births).
Notably, two adjacent, low-income southern states had significantly different outcomes. Alabama had 41 deaths per 185,549 live births for non-Hispanic black infants and 46 deaths per 362,404 live births for non-Hispanic white infants. Mississippi, however, had 115 deaths per 176,825 live births for non-Hispanic black infants and 93 deaths per 206,819 live births for non-Hispanic white infants.
"Despite increased public health efforts for education about safe sleep practices, we have seen significant surges in infant deaths from accidental strangulation and suffocation," said Joanna Drowos, D.O., M.P.H., M.B.A, lead author, associate dean for faculty affairs, and associate chair, Department of Integrated Medical Science, FAU's Schmidt College of Medicine. "By gaining a deeper understanding of the epidemiology, including both risk and protective factors, public health professionals can tailor messages and programs to reach a diverse group of mothers to help reduce deaths related to this preventable tragedy."
The study also shows that mortality rates increased as live birth order increased, especially among young mothers. Non-Hispanic black infants who were the fourth live births for mothers 15 to 24 years old had the highest rate of all of the sub-groups analysed (116.7 per 100,000 live births), followed by non-Hispanic black infants from the same maternal age group who were the fifth or sixth live-born infant. Among non-Hispanic white mothers 15 to 24 years old, the death rate for infants who were the fifth or sixth live birth was 87.1 per 100,000 live births.
In Michigan, non-Hispanic black infants who were the fourth to sixth live births for mothers 15 to 29 years old had an infant mortality rate of 259 per 100,000 live births and 78.9 per 100,000 live births for non-Hispanic white infants (2007-2016 inclusive). For non-Hispanic black infants who were the fifth or sixth live births occurring to such mothers, the rate was 301 per 100,000 live births.
According to the Centers for Disease Control and Prevention (CDC), in 2016, accidental suffocation and strangulation in bed accounted for 25 percent (900) of the approximately 3,600 sudden unexpected infant deaths in the U.S.
"We must conduct the rigorous studies to curb these alarming increases in overall deaths and racial inequalities," said Charles H. Hennekens, M.D., Dr.P.H., co-author, first Sir Richard Doll Professor and senior academic advisor in FAU's Schmidt College of Medicine. "Future areas of research might include examining family and cultural differences around sleep, local pediatrician practices, available social services, and policies to combat these alarming increases."
For the study, researchers used the National Center for Health Statistics Multiple Cause of Death Records from 1999 to 2016. Infant births, infant deaths and infant mortality rates from 1999 to 2016 were obtained from Linked Birth/Infant Death Records as presented on the CDC's Wide-ranging ONline Data for Epidemiologic Research (WONDER).
Study co-authors are Maria C. Mejia de Grubb, M.D., M.P.H.; Jason L. Salemi, Ph.D., M.P.H.; Robert S. Levine, M.D.; and Roger J. Zoorob, M.D., M.P.H., all with Baylor College of Medicine; and Aaron Fils, a pre-medical student at the University of Miami.
About the Charles E. Schmidt College of Medicine:
FAU's Charles E. Schmidt College of Medicine is one of approximately 152 accredited medical schools in the U.S. The college was launched in 2010, when the Florida Board of Governors made a landmark decision authorizing FAU to award the M.D. degree. After receiving approval from the Florida legislature and the governor, it became the 134th allopathic medical school in North America. With more than 70 full and part-time faculty and more than 1,300 affiliate faculty, the college matriculates 64 medical students each year and has been nationally recognized for its innovative curriculum. To further FAU's commitment to increase much needed medical residency positions in Palm Beach County and to ensure that the region will continue to have an adequate and well-trained physician workforce, the FAU Charles E. Schmidt College of Medicine Consortium for Graduate Medical Education (GME) was formed in fall 2011 with five leading hospitals in Palm Beach County. In June 2014, FAU's College of Medicine welcomed its inaugural class of 36 residents in its first University-sponsored residency in internal medicine and graduated its first class of internal medicine residents in 2017.
About Florida Atlantic University:
Florida Atlantic University, established in 1961, officially opened its doors in 1964 as the fifth public university in Florida. Today, the University, with an annual economic impact of $6.3 billion, serves more than 30,000 undergraduate and graduate students at sites throughout its six-county service region in southeast Florida. FAU's world-class teaching and research faculty serves students through 10 colleges: the Dorothy F. Schmidt College of Arts and Letters, the College of Business, the College for Design and Social Inquiry, the College of Education, the College of Engineering and Computer Science, the Graduate College, the Harriet L. Wilkes Honors College, the Charles E. Schmidt College of Medicine, the Christine E. Lynn College of Nursing and the Charles E. Schmidt College of Science. FAU is ranked as a High Research Activity institution by the Carnegie Foundation for the Advancement of Teaching. The University is placing special focus on the rapid development of critical areas that form the basis of its strategic plan: Healthy aging, biotech, coastal and marine issues, neuroscience, regenerative medicine, informatics, lifespan and the environment. These areas provide opportunities for faculty and students to build upon FAU's existing strengths in research and scholarship. For more information, visit fau.edu.