News Release 

New data fills research gaps on weight loss experiences for minority groups

Report suggests tailoring interventions can improve health outcomes

The Obesity Society

SILVER SPRING, Md.--The use of intensive lifestyle interventions focused on altering dietary and physical activity habits using behavioral strategies can produce sustained weight loss among African Americans and Hispanics who have type 2 diabetes (T2D), according to a new study published online today in Obesity, the flagship journal of The Obesity Society.

Researchers explain that rates of obesity and T2D are particularly high among African American and Hispanic adults, and underlie substantial health disparities observed in these populations. Limited published data are available on the specific components of effective lifestyle interventions for minority men and women with T2D or the individual behavioral weight control practices associated with successful weight control, leaving gaps in the scientific literature and a lack of guidance about how to tailor intervention approaches for these high-risk populations.

"The current research points to key lifestyle intervention program elements that are associated with successful, long-term, weight control in minority men and women, as well as specific behavioral strategies that could be emphasized within individual sub-groups to optimize weight loss outcomes," said one of the study's authors Delia West, PhD, of the University of South Carolina Arnold School of Public Health in Columbia.

To expand previous findings, West and colleagues examined information collected as part of the Action for Health in Diabetes (Look AHEAD) Trial. Researchers studied 2,361 African American, Hispanic, and non-Hispanic white men and women, who had obesity and T2D, and were randomized to receive the Intensive Lifestyle Intervention (ILI). Participants were given a weight loss goal of 10 percent to be achieved through decreased calorie and fat intake; and increased physical activity. Changes in weight were measured at one, four and eight years.

Study participants were provided weekly group and individual counseling sessions for the first six months (three group and one individual session), followed by three sessions per month (two group and one individual session) for the second six months. Structured meal plans and meal replacements were provided at no cost to facilitate weight loss goals. Participants were to engage in at least 175 min./week of unsupervised, moderate-intensity, physical activity such as brisk walking. Researchers instructed participants to record dietary intake, calculate calorie and fat consumption, log weight and monitor physical activity on a daily basis using a paper-based journal. Behavioral strategies included goal setting, problem solving, social support and relapse prevention.

Results revealed high attendance at individual and group intervention counseling sessions. According to West and colleagues, individual session attendance appeared to be particularly important for successful weight loss among Hispanic and African American men, while group attendance was strongly associated with weight loss for Hispanic and African American women.

The study's authors also found meal replacement use was high during the first year of intervention. Researchers said, however, that meal replacements were not an independent predictor of weight loss in Hispanics or African American men, but were strongly associated with poorer weight loss outcomes among African American women.

Researchers found daily monitoring of body weight associated with successful weight loss in the first year of the lifestyle intervention among African American men and women with T2D and it continued to be important for weight maintenance among African American women, but was not as strongly associated with weight loss outcomes among Hispanic men and women with T2D.

"The ILI is noteworthy in that it successfully produced weight loss over eight years in a diverse sample of individuals with diabetes, with more than a third of individuals self-identifying as a member of a racial or ethnic minority group. Furthermore, 40 percent of participants were male, which contrasts with most previous weight control studies that enrolled few men," West and colleagues write in the report.

Jamy Ard, MD, FTOS, professor of epidemiology and prevention at Wake Forest University School of Medicine in Winston-Salem, NC, who was not associated with the research, said the study has two important implications.

"First, it demonstrates that people respond differently to various treatments, and as a result, we should continue seeking personalized treatment approaches, using different tools in the behavioral toolbox based on individual characteristics. Secondly, this work shows that behavioral treatment can be effective for a diverse population, especially when treatment engagement is frequent and continues long term. If we want to address disparities and engage diverse populations in effective obesity treatment, it will likely depend on providing access to care and insurance coverage for these treatments," said Ard.

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Other authors of the study include Gareth Dutton of the University of Alabama at Birmingham; Linda M. Delahanty, Massachusetts General Hospital and Harvard Medical School in Boston; Helen P. Hazuda of University of Texas Health Science Center, San Antonio; Amy D. Rickman, Slippery Rock University in Pennsylvania; William C. Knowler, National Institutes of Diabetes and Digestive and Kidney Diseases in Phoenix, AZ; Mara Z. Vitolins and Rebecca H. Neiberg, Wake Forest University in Winston-Salem, NC; Anne Peters, University of Southern California in Los Angeles; Molly Gee, Baylor College of Medicine in Texas; Maria Cassidy-Begay, Indian Health Service in Shiprock, NM; and the Look AHEAD Research Group.

This work was funded by the National Institutes of Health (NIH) through cooperative agreements with the National Institute of Diabetes and Digestive and Kidney Diseases. Additional funding was provided by the National Heart, Lung and Blood Institute; National Institute of Nursing Research; National Center on Minority Health and Health Disparities; NIH Office of Research on Women's Health; and the Centers for Disease Control and Prevention.

The study, titled "Weight Loss Experiences of African American, Hispanic and Non-Hispanic White Men and Women with Type 2 Diabetes: The Look AHEAD Trial," will be published in the August 2019 print issue of Obesity.

The Obesity Society (TOS) is the leading organization of scientists and health professionals devoted to understanding and reversing the epidemic of obesity and its adverse health, economic and societal effects. Combining the perspective of physicians and other clinicians, scientists, policymakers and patients, TOS promotes innovative research, education, and evidence-based clinical care to improve the health and well-being of all people with obesity. For more information, visit http://www.obesity.org and connect with us on Facebook, Twitter and LinkedIn.

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