News Release 

Optimism associated with lower risk of heart disease, early death

JAMA Network Open

Bottom Line: Optimism was associated with lower risk of cardiovascular events and less risk of overall death in this observational study. The study, called a systematic review and meta-analysis, combined results from 15 studies (10 studies reported data on cardiovascular events and nine reported data on all-cause mortality) with nearly 230,000 participants and an average follow-up of nearly 14 years. Limitations of the study include wide variation in ages of the participants; the inability to account for individual mitigating factors such as smoking, diabetes and hypertension; and a study design that doesn't permit causal inferences to be made. Future studies should examine what might explain this association, as well as investigate the potential benefits of interventions that could promote optimism and reduce pessimism.

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

Authors: Alan Rozanski, M.D., Mount Sinai St. Luke's Hospital, New York, and coauthors

(doi:10.1001/jamanetworkopen.2019.12200)

Editor's Note: Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.

 #  #  #

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time: http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2019.12200?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=092719

About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. Every Wednesday and Friday, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

###

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.