News Release 

GARDP partners with Japanese pharmaceutical in pursuit of new antibiotics

Global Antibiotic Research & Development Partnership

[Geneva/Tokyo - 12 March 2020] The Global Antibiotic Research and Development Partnership (GARDP) has today announced an agreement with Daiichi Sankyo for GARDP to access and screen the Daiichi Sankyo chemical library. The library will be tested by Institut Pasteur Korea with the goal of discovering novel antibacterial compounds. The agreement sees Daiichi Sankyo join Eisai and Takeda as part of an AMR Screening Consortium, which aims to accelerate GARDP efforts to identify compounds for development into treatments for drug-resistant infections.

Antimicrobial resistance is a major and rapidly growing public health concern and has been identified by the World Health Organization (WHO) as among the greatest threats to global health. Each year 700,000 people die due to drug-resistant infections. Without urgent action to develop new antimicrobial treatments, this number is projected to increase exponentially.

GARDP will test compounds from the Daiichi Sankyo chemical library, which have never been screened for antibacterial activity, against drug-resistant bacteria identified as a critical priority on the WHO priority pathogens list. Through the screening, GARDP hopes to identify novel compounds for further optimization and development.

"GARDP's partnership with Daiichi Sankyo gives GARDP the opportunity to screen a proprietary library that otherwise would not be tested for antibacterial activity," said Laura Piddock, GARDP Director of Scientific Affairs. "The AMR Screening Consortium is a wonderful opportunity to discover novel compounds to potentially develop into life-saving treatments for drug-resistant infections."

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About the AMR Screening Consortium

The AMR Screening Consortium is an agreement between the Global Antibiotic Research and Development Partnership (GARDP) and pharmaceutical companies Daiichi Sankyo, Eisai and Takeda, together with Institut Pasteur Korea, an infectious disease-focused research institute, to access and screen the companies' chemical libraries in search of novel antibacterial compounds. The AMR Screening Consortium seeks to accelerate GARDP efforts to identify compounds for development into treatments for drug-resistant infections and supports the pharmaceutical sector in staying engaged in antibiotic research and development.

About GARDP

The Global Antibiotic Research and Development Partnership (GARDP) is a not-for-profit developing new and improved treatments for drug-resistant infections, while working to ensure responsible use and sustainable access. Created by the WHO and Drugs for Neglected Diseases Initiative, GARDP is an essential element of the Global Action Plan on Antimicrobial Resistance. http://www.gardp.org

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