What The Study Did: This randomized clinical trial assessed the effect of treating patients with relapsing multiple sclerosis with a therapeutic hookworm infection compared with placebo. Some studies have suggested that gut worms induce immune responses that can protect against multiple sclerosis.
Authors: Cris S. Constantinescu, M.D., Ph.D., and David I. Pritchard, Ph.D., of the University of Nottingham in Nottingham, England, are the corresponding authors.
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(doi:10.1001/jamaneurol.2020.1118)
Editor's Note: The article includes conflicts of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflicts of interest and financial disclosures, and funding and support.
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Journal
JAMA Neurology