Enzyme inhibitors play a pivotal role in pharmaceutical and nutraceutical industries. The primary understanding of the action of inhibitors helps pharmacologists during the design process for developing new therapeutic drugs. Most drugs treat various chronic and life threatening diseases owing to their specificity and the potency of enzymes which they can inhibit. Enzyme inhibitors are used to screen various levels of diseases which propel the growth of inhibitors. The potential for enzyme inhibitors in the therapeutics market is very high as the biochemical properties and classes of enzyme inhibiting products are readily available.
The other broad aspect of enzyme inhibition is their application in analytical sensors. These sensors assist in monitoring various environmental factors. Understanding the mechanism of inhibition and regeneration of enzymes is a general problem of great importance for many biochemists and biotechnologists especially when using immobilized enzymes.
This reference compiles applied information about enzyme inhibitors used in medicine and environmental monitoring applications. Chapters presented in this volume cover special topics including biosensors, crop improvements in agriculture, biofuel production, pesticide and heavy metal detection, and drug therapy for human diseases such as breast cancer, neurological diseases and viral infections. The collection of topics in this volume makes it an informative resource for readers at all academic levels on the applications of enzyme inhibitors in medicine and environmental sciences.
About the Editors:
Dr. G. Baskar completed his Ph.D. from Anna University, Chennai. He is currently working as a Professor of Biotechnology in St. Joseph's College of Engineering, Chennai, India. He has published more than 150 research and review articles in National and International Journals, published 15 chapters in edited books and edited 3 books. His current research areas are food toxicology, biofuels and bioenergy, nanocatalysis, therapeutic proteins, microbial enzymes, nanomedicine and bioremediation. He is an active life member of various national and international professional bodies. Dr. Baskar is also the editorial board member of several journals, recipient of Outstanding Reviewer Awards from various Elsevier Journals. He has been honored with several awards in his field of research.
Dr. K. Sathish Kumar is an Associate Professor at the Department of Chemical Engineering, SSN College of Engineering, Chennai, India. He completed his PhD from Anna University Chennai. He has published over 40 research publications in refereed international journals and in proceedings of international conferences. He is a recognized supervisor of Anna University of Technology Chennai. His current research work includes synthesis of bimetallic particle, development of new nanocapsules for drug delivery, use of metallic nanoparticles as an adsorbent and its applications in water treatment. He is a life member of Indian Society for Technical Education (ISTE) and Biotech Research Society, India (BRSI).
Dr. K. Tamilarasan is currently working as an Associate Professor at the Department of Chemical Engineering at SRM Institute of Science and Technology, Kattankulathur, Tamilnadu, India. He completed his Ph.D. in Biochemical Engineering (2012), Anna University, Chennai, India. His major research areas are bioenergy, platform chemical synthesis and photochemical degradation. He has published more than 30 publications in the International and National Journals and few book chapters. He had collaborative research work in the field of carbohydrate chemistry at University of Minnesota, USA. He is associated with several society including Indian Institute of Chemical Engineers (IIChE) and Biotech Research Society, India (BRSI).
Keywords: Enzyme inhibitors, analytical sensors, environmental sciences, immobilized enzymes, biochemical properties, biosensors, biofuel production, drug therapy
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