News Release

Beta (South Africa) variant may increase risk for COVID-19 hospitalization and death, large-scale South African study suggests

Peer-Reviewed Publication

European Society of Clinical Microbiology and Infectious Diseases

For interviews with the report authors, please contact Dr Waasila Jassat, National Institute for Communicable Diseases of the National Health Laboratory Service, South Africa E) waasilaj@nicd.ac.za T) +27(0)82 927 4138

Alternative contact in the ECCMID Press Room: Tony Kirby T) + 44(0)7834 385827 E) tony@tonykirby.com or Rachael Davies T) +44(0)797 456 0784 E) rachaelvdavies@hotmail.co.uk

Notes to editors:

[1] Wave 1: (14721 deaths/59617625 SA population)*100,000 = 24.7 deaths per 100,000 people Wave 2: (28682 deaths/59617625 SA population)*100,000 = 48.1 deaths per 100,000 people

[2] Coronavirus deaths by country in Africa 2021 | Statista / South Africa | UNAIDS https://www.statista.com/statistics/1170530/coronavirus-deaths-in-africa/

[3] See table 1; weeks with very high admissions; 27,949 deaths among 104,058 patients with outcomes (case fatality risk 26.9%). Weeks with low admissions; 8,985 deaths among 50,840 patients with outcomes (case fatality risk 17.7%).

The surveillance was funded by the National Institute for Communicable Diseases and the South African Government. The study did not receive any additional funding.

The authors declare no conflicts of interest.

The Lancet Global Health: Difference in mortality among individuals admitted to hospital with COVID-19 during the first and second waves in South Africa: a cohort study

Article available under embargo at (journalist only link): http://www.thelancet-press.com/embargo/tlgh.pdf

Appendix available under embargo at (journalist only link): http://www.thelancet-press.com/embargo/tlghAPPX.pdf

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