Researchers from the Center for Precision Disease Modeling at the University of Maryland School of Medicine (UMSOM) have uncovered a mechanism that appears to explain how certain genetic mutations give rise to a rare genetic kidney disorder called nephrotic syndrome.
A new review examined two decades of research on how people develop trust in AI. The authors concluded that the way AI is represented, or 'embodied,' and AI's capabilities contribute to developing trust. They also proposed a framework that addresses the elements that shape users' cognitive and emotional trust in AI, which can help organizations that use it.
US policymakers considering physical distancing measures to slow the spread of COVID-19 face a difficult trade-off between closing schools to reduce transmission and new cases, and potential health-care worker absenteeism due to additional childcare needs that could ultimately increase mortality from COVID-19, according to new modelling research published in The Lancet Public Health journal.
Now a team of researchers at the University of Illinois, led by physicist Vidya Madhavan, in collaboration with researchers from the National Institute of Standards and Technology, the University of Maryland, Boston College, and ETH Zurich, have used high-resolution microscopy tools to peer at the inner-workings of an unusual type of superconductor, uranium ditelluride (UTe2). Their measurements reveal strong evidence that this material may be a natural home to an exotic quasiparticle that's been hiding from physicists for decades.
You might have heard that COVID-19 vaccine trials are underway in Seattle. What exactly is being tested? How much longer will these tests take? And when can we expect a vaccine against the novel coronavirus? We chat with Benjamin Neuman, Ph.D., one of the world's experts on coronavirus, and Daniel Wrapp, one of the scientists who mapped the structure of the protein that the coronavirus uses to infect your cells, to help us answer these questions: https://youtu.be/gDY8pH6OWBc.
A previous study has shown that a type of squill growing in Madeira produces a chemical compound that may be useful as a medicinal drug. But a new study from researchers at Uppsala University has shown that this is probably not true: instead, the plant had likely accumulated antibiotics from contaminated soil.
An article published in the Journal of Medicinal Chemistry shows a new family of molecules with high affinity to join imidazoline receptors, which are altered in the brain of those patients with neurodegenerative diseases such as Alzheimer's, Parkinson's and Huntington's. According to the preclinical study, the merge of these specific ligands to I2 receptors improves cognitive skills and some biomarkers which are indicators of brain neurodegenerative processes in murine models.
Scientists in EMBL Barcelona's Ebisuya group, with collaborators from RIKEN, Kyoto University, and Meijo Hospital in Nagoya, Japan, have studied oscillating patterns of gene expression, coordinated across time and space within a tissue grown in vitro, to explore the molecular causes of a rare human hereditary disease known as spondylocostal dysostosis. Their results are published in Nature.
A Nordic study sheds new light on the role of northern peatlands in regulating the regional climate. According to the researchers, peatlands will remain carbon sinks until the end of this century, but their sink capacity will be substantially reduced after 2050, if the climate warms significantly.
Melatonin controls the body clock -- high melatonin levels make us feel tired in the evening. However, the hormone also plays an important role in animals' biological rhythms. Artificial light at night -- light pollution -- can suppress the production of melatonin in fish, even at very low light intensities, a finding established by researchers from the Leibniz-Institute of Freshwater Ecology and Inland Fisheries (IGB).