Antimicrobial resistant genes found in wastewater samples from a South African city
Peer-Reviewed Publication
Updates every hour. Last Updated: 31-Mar-2026 03:16 ET (31-Mar-2026 07:16 GMT/UTC)
In a study led by researchers from the NRF-DSTI research chair in African Microbiome Innovation at Stellenbosch University (SU), scientists investigated how antimicrobial resistance genes behave in WWTPs and rivers in a large urban city in South Africa. Because of the lack of such studies in Africa, and the potential implications for water reuse, Dr Makumbi and his co-authors conducted a microbiome study to get a sense of what is happening at WWTWs and connected river systems in South Africa.
A 16-year study of nearly 400,000 km of road surveys reveals widespread declines in South Africa’s raptors and other large birds, with half of the species showing significant population losses. The findings highlight urgent conservation concerns and the need for robust, long-term monitoring to protect these ecologically vital predators.
A paper published in the journal Proceedings B of the Royal Society describes the discovery of a new species of magic mushroom – Psilocybe ochraceocentrata – from the grasslands of South Africa and Zimbabwe. So named because of the ochre-yellow colour at the center of the mushroom cap, P. ochraceocentrata last shared a common ancestor with P. cubensis approximately 1.5 million years ago.
A new digital reconstruction of the face of the 3.67‑million‑year‑old Australopithecus fossil, Little Foot, provides new insight into the evolution of the human face.
The new findings, published in Comptes Rendus Palevol, offer fresh insight into the diversity of the fossil hominin (i.e., extant human and their ancestors and relatives) face across Africa 4-3 million years ago.
A PhD candidate at the Wits Advanced Drug Delivery Platform (WADDP), University of the Witwatersrand, has been awarded the 2026 South African Medical Research Council (SAMRC) Institutional Clinician Researcher Development Programme Scholarship to advance research into targeted nanoparticle therapies for glioblastoma — one of the most aggressive and lethal forms of brain cancer.
Michael Gomes, who is simultaneously completing medical training and a PhD, is investigating innovative nanoscale drug delivery systems designed to overcome one of the biggest challenges in brain cancer treatment: the blood–brain barrier. This protective barrier prevents many chemotherapy drugs from reaching tumours at effective concentrations, contributing to poor survival outcomes. Most glioblastoma patients survive only 12 to 18 months after diagnosis.
Gomes’s research compares three nanoparticle platforms — liposomes, polymer-based particles, and polydopamine nanoparticles — to determine which most effectively delivers chemotherapy to brain tumours while limiting systemic toxicity. His work places particular emphasis on polydopamine nanoparticles, a relatively unexplored system inspired by dopamine, a molecule naturally present in the brain.
A new review from the Antiviral Gene Therapy Research Unit (AGTRU) at the University of the Witwatersrand highlights how viral mimic systems and related technologies could accelerate the development of vaccines and antiviral therapies, particularly in low-resource settings. Published in the journal Infection, the review describes safe, virus-like platforms that replicate key features of dangerous pathogens without the ability to cause disease.
Conventional antiviral research often requires biosafety level-3 laboratories, which are expensive, tightly regulated, and scarce. Viral mimic systems overcome this bottleneck by enabling scientists to study infection, screen drug candidates, and compare immune responses in standard biosafety level-2 facilities. This allows promising therapies to move more quickly from laboratory testing to clinical development.
The review focuses on technologies such as pseudo-typed viruses and virus-like particles that reproduce the early stages of infection. More advanced models incorporate all four structural proteins of SARS-CoV-2, offering a more realistic picture of viral behaviour and helping researchers design broader, more durable vaccines that remain effective against emerging variants.