A single-celled predator maintains stolen chloroplasts with its own proteins, linking the host cell and stolen organelles at the molecular level. This process, now supported by biochemical evidence, may offer clues to early steps in the evolution of plant cells.

Researchers introduce a novel generative AI-driven framework, MMCN (Memory-aware Multi-Conditional generation Network), for forecasting future urban layouts by jointly considering building density, building height, transportation networks, and historical development patterns. Leveraging a generative architecture-enhanced diffusion model with multi-conditional control, semantic prompt fusion, and spatial memory embedding, MMCN offers a novel approach to modeling complex urban evolution. This framework provides a powerful tool to explore sustainable urban development, demonstrating AI’s transformative potential in urban design.

Interactions between diet and the gut microbiome have been shown to have broad roles in shaping host metabolism and health. Now, researchers at the Human Biology Microbiome Quantum Research Center (WPI-Bio2Q, directed by Kenya Honda, M.D., Ph.D., co-senior author of the study) and Keio University, together with researchers from City of Hope and the Broad Institute, show how specific gut microbes are able to interpret diet and subsequently drive the conversion of white adipose tissue into beige fat, a metabolically active form of fat that burns energy instead of storing it.

 

The study, which has been published in Nature, also identified the molecular pathways that connect these aspects of dietary protein intake, microbial metabolism, and the host’s fat-burning response.

 

“These findings show, in a mechanistic way, how gut microbes are able to act as an important mediator of dietary cues, and how these bacteria are able to produce signals that shape host metabolism” said Scott Behie, member of WPI-Bio2Q and co-author of the study.

Japan’s Ministry of Internal Affairs and Communications has featured “Shika Sonic” and “Bird Sonic” as examples of academia–industry collaboration tackling regional challenges. Developed by T.M.WORKS and evaluated by Okayama University of Science, the systems are being used at airports, along railways, and on roads to help reduce wildlife-related damage. While the technology has shown effectiveness, further improvements are needed to address non-target species and equipment damage caused by birds.

Cryopreservation is not a new technology, but there is still much to explore and perfect in the field. Current methods use slow freezing, a method that is conducive to ice formation, cell dehydration and an increase in cryoprotective agents (CPAs). These are not ideal circumstances for achieving immaculately cryopreserved cells. Researchers from the University of Tokyo use vitrification, a process that transforms a substance into a noncrystalline solid by rapid cooling. This cooling yields favorable outcomes in biological samples, even those that are typically difficult to freeze and thaw successfully. Despite challenges within this method, the future of regenerative medicine research may be greatly, and positively, impacted by the use of vitrification for cell cryopreservation.

A newly developed 2.4 GHz Wi-Fi receiver from Science Tokyo can survive radiation levels found inside nuclear reactors. With a radiation tolerance of up to 500 kGy, the chip allows robots used in nuclear plant decommissioning to be controlled wirelessly. Such receivers reduce the need for wired connections and can improve worker protection during decommissioning and cleanup operations at contaminated sites such as the Fukushima Daiichi Nuclear Power Plant.

Kyoto, Japan -- In April 2021 the United States hosted the Leaders Summit on Climate, where many of the world's most powerful countries -- and largest carbon emitters -- committed to net-zero emissions targets. Many also made pledges to divest from fossil fuels and invest in green finance. Since then, the capacity for renewable energy and sales of electric vehicles have increased. Yet progress toward system-level transformations is still moving at a snail's pace.

Meeting these targets will depend on commitments from more than just the wealthiest nations. Given the size of their populations, economies, and greenhouse gas emissions, developing economies in Southeast Asia will also play essential roles in the transition to net-zero.

In a new book, a collaborative team of researchers including Akihisa Mori from Kyoto University, focuses on the net-zero transition in Southeast Asia, applying the lessons from the Leaders Summit on Climate to these countries. The researchers wanted to understand whether financial pledges, such as fossil fuel divestment and green finance, can help financial systems overcome the tradeoff between net-zero transitions and sustainable development in emerging markets and developing economies.

Researchers led by Hiroki R. Ueda at the University of Tokyo developed comprehensive 3D cellular atlases spanning all organs and the entire body, termed the CUBIC Organ/Body Atlas. By optimizing the CUBIC tissue-clearing method and establishing high-resolution whole-body imaging, the group mapped the spatial positions of individual cells and enabled quantitative comparisons across samples. This platform enables whole-body–scale quantitative analysis, integration with molecular data, and opens new opportunities for 3D biological and pathological analysis.

A team of researchers led by the University of Tokyo Kavli Institute for the Physics and Mathematics of the Universe (Kavli IPMU, WPI) Project Assistant Professor Elisa Ferreira has shown that a discrepancy in a key cosmic measurement in the early universe originates from a subtle statistical interplay between measurements of the cosmic microwave background (CMB) and baryon acoustic oscillations (BAO).

Researchers at AIMR engineered cultured neuronal networks with brain-like hierarchical modularity and directional connectivity using microfluidic devices. Integrating experiments with computational modeling, they demonstrated that directional connections suppress excessive synchrony and enhance balanced network dynamics. This platform advances understanding of brain organization and enables applications in drug discovery and brain-inspired biocomputing systems.