Genomic Fault Zones Come and Go (2 of 2) (IMAGE) University of California - San Diego Caption In this graphic, the colored marks represent positions of the putative fragile regions in the human genome. The Turnover Fragile Breakage Model suggests that these regions likely form (still active) fragile regions in the human genome. The graphic above is from the new Genome Biology paper in which the Turnover Fragile Breakage Model (TFBM) is presented. According to the TFBM, the fragile regions in mammalian genomes that are thought to play a key role in evolution go through a "birth and death" process. Credit Credit: Max Alekseyev / Pavel Pevzner Usage Restrictions Credit: Max Alekseyev / Pavel Pevzner License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.