Let-7 and Neuroblastoma Survival (IMAGE) Boston Children's Hospital Caption These survival curves, based on 202 patients with neuroblastoma, show that chromosomal let-7 loss reduces survival in both MYCN-amplified and non-MYCN-amplified neuroblastoma. With a larger patient sample, curves such as this could help predict patient survival based on these genetic parameters. Credit Courtesy John Powers, PhD Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.