Researchers at the Indiana University School of Medicine, Eskenazi Health, Regenstrief Institute and other partners have demonstrated the feasibility of conducting dementia prevention trials among older adults with limited formal education, a group at heightened risk for Alzheimer’s disease and related dementias.

The MINDSpeed trial, a randomized study, tested whether a diet rich in polyphenols, which are plant-based compounds found in foods like nuts and berries, and online speed-of-processing cognitive training could improve cognition in older adults with 12 or fewer years of education.