A new study meticulously sampled different lung regions in people with cystic fibrosis to understand why infections persist after treatment with new drugs called modulators. These drugs are not curative, but help improve symptoms by addressing the underlying physiological flaw in this genetic condition. Unexpectedly, the new findings suggest that lung damage might not be the main cause of infection persistence. It might be possible that the bacteria is adapting in new ways to resist clearance even when the lungs are being treated with the best drugs available. 

A new discovery by Van Andel Institute scientists reveals that glucose, an essential cellular fuel that powers immune cells, also aids in T cells’ internal communication and boosts their cancer-fighting properties. The findings may help optimize T cells’ ability to combat cancer and other diseases.