A McGill University-led clinical trial is the first in humans to show online brain training exercises can improve brain networks affecting learning and memory.

The study found 10 weeks’ use of the game-like app BrainHQ by older adults enhanced cholinergic function, a chemical system in the brain that typically declines with age and influences attention, memory and decision-making.

Researchers from The University of Osaka in collaboration with Baylor College of Medicine have developed a new therapy for a severe form of male infertility called non-obstructive azoospermia (NOA). Using lipid nanoparticles (LNPs) to deliver specific mRNA into the testes of infertile mice, they were able to restart sperm production. The sperm produced were then used in intracytoplasmic sperm injection (ICSI) to successfully generate healthy and fertile offspring. The findings provide a crucial proof-of-concept for treating male infertility caused by genetic defects.