Using a computational strategy that allows them to combine information from many large datasets, MIT researchers have identified several new potential targets for Alzheimer’s disease.

Fatal drug overdoses among youth aged 15 to 24 in the United States involving synthetic opioids alone—not mixed with other substances—soared by 168 percent over the five-year time period of 2018 to 2022, a new study shows. Publishing online May 20 in the journal Pediatrics, the work also found that youth overdose rates and drug combinations varied significantly across age, sex and race/ethnicity.