NIH-funded exploratory study to seek possible targets for treating alcohol use disorder
Grant and Award Announcement
Updates every hour. Last Updated: 16-Dec-2025 09:11 ET (16-Dec-2025 14:11 GMT/UTC)
Alcohol use disorder (AUD) affects approximately 14.1 million people in the U.S. Pharmacological treatment options for AUD have advanced only minimally since 2004, underscoring the urgent need for novel therapeutic targets. To uncover some of these potential targets, the National Institute on Alcohol Abuse and Alcoholism awarded a two-year grant to TTUHSC’s Dawei Li, Ph.D., who will seek to identify new neurobiological factors for potential intervention, including a possible link between endogenous retroviruses and neuroinflammation.
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Researchers at Wayne State University will work with Michigan agencies and education partners to improve access to school-based substance use prevention and treatment programs for adolescents who are at risk of substance misuse and substance use disorders (SUDs) with the help of a NIH R61 grant.
Jiahe Zhang, PhD, of the Department of Psychiatry at Mass General Brigham, is the lead author of the paper published in Nature Neuroscience, “Cortical and subcortical mapping of the human allostatic-interoceptive system using 7 Tesla fMRI.”
Lisa Feldman Barrett, PhD, and Marta Bianciardi, PhD, of the Department of Radiology at Mass General Brigham are co-senior authors. Barrett is also affiliated with the Department of Psychiatry at Mass General Brigham.