A widely prescribed diabetes drug may be sabotaging one of the most trusted strategies for preventing the disease: exercise.

That is the conclusion of a Rutgers-led study published in The Journal of Clinical Endocrinology & Metabolism, which found that metformin blunts critical improvements in blood vessel function, fitness and blood sugar control that normally come from working out.

Researchers at the University of Maryland School of Medicine’s Center for Vaccine Development and Global Health (CVD) reported encouraging results from an early phase clinical trial that found an experimental intranasal vaccine triggered a broad immune response against multiple strains of H5N1 “bird flu”. The study, published today in the journal Nature Communications, [DK1] highlights the potential of mucosal immunization strategies--where vaccines are sprayed into the nostrils--to prime immune defenses against diverse influenza strains.

People with signs of damage to their heart during middle age are more likely to develop dementia in later life, according to a new study led by UCL (University College London) researchers.