In a new study, University of Arizona researchers created a model for cutaneous squamous cell carcinoma, a type of skin cancer, and identified two mutated tumor proteins, or neoantigens, that contain features of good candidates for a vaccine. At the same time, they used artificial intelligence to create 3D models to help them understand and predict which neoantigens could provoke T cells, a type of white blood cell critical to the immune system, to attack the cancer. 

Northwestern University researchers have captured a detailed look at one of the body’s major heat sensors, revealing how it turns on when temperatures rise. They found the part of the sensor inside the cell is important for detecting and responding to heat. Sensor also is linked to chronic pain and epilepsy, opening the door to new treatments.