EurekAlert! National Institutes of Health

Latest news releases from NIH-funded organizations

Funded Research News

Updates every hour. Last Updated: 3-May-2025 11:09 ET (3-May-2025 15:09 GMT/UTC)

10-Mar-2025

Scientists create a universal vascular graft with stem cells to improve surgery for cardiovascular disease

Morgridge Institute for Research
Peer-Reviewed Publication

Scientists at the Wisconsin National Primate Research Center and the Morgridge Institute for Research at the University of Wisconsin–Madison developed a universal, small diameter, vascular graft using stem cell-derived arterial endothelial cells that could advance the field of vascular bypass surgery as a treatment to combat cardiovascular disease.

Journal: Cell Reports Medicine
Funder: NIH/National Heart, Lung and Blood Institute, NIH/National Institutes of Health

10-Mar-2025

Female sex hormone protects against opioid misuse, rat study finds

WashU Medicine
Peer-Reviewed Publication

According to a new study by WashU Medicine researchers, male and female rats with a chronic pain condition release different amounts of dopamine when given fentanyl because of sex hormones. The findings might help explain why men have higher rates of opioid use and overdose deaths.

Journal: Neuron
Funder: NIH/National Institutes of Health, W. M. Keck Foundation, Brain and Behavior Research Foundation

10-Mar-2025

Breakthrough combination therapy tackles drug resistance in lung cancer with common KRAS mutation

Virginia Commonwealth University
Peer-Reviewed Publication

A breakthrough in lung cancer treatment may be on the horizon. Scientists at VCU Massey Comprehensive Cancer Center have uncovered a powerful combination therapy leveraging sotorasib—an FDA-approved drug in the market—and an experimental drug called FGTI-2734, which could make precision medicine more effective for patients with a highly resistant form of lung cancer. The study, featured on the cover of the Journal of Thoracic Oncology, reveals a potential game-changer for patients battling tumors with the KRAS G12C mutation—a driver in about 14% of non-small cell lung cancers.

Journal: Journal of Thoracic Oncology
Funder: NIH/National Cancer Institute

10-Mar-2025

Chronic stress and obesity work together to accelerate pancreatic cancer development and growth, study finds

University of California - Los Angeles Health Sciences
Peer-Reviewed Publication

A new study led by UCLA investigators suggests that chronic stress and an unhealthy diet may work together to fuel the early development of pancreatic cancer, shedding light on how lifestyle factors contribute to one of the deadliest malignancies.

Journal: Molecular Cancer Research
Funder: NIH/National Cancer Institute, NIH/National Institute of Allergy and Infectious Diseases, Hirshberg Foundation for Pancreatic Cancer Research

10-Mar-2025

Cryo-electron microscopy reveals hidden mechanics of DNA replication, sheds new light on cancer target

Memorial Sloan Kettering Cancer Center
Peer-Reviewed Publication

MSK researchers shed new light on G-quadruplexes, a type of secondary DNA structure that has attracted attention as a potential therapeutic target in cancer.

Journal: Science
Funder: NIH/National Institutes of Health, NIH/National Cancer Institute