CRISPR’s efficiency triples with DNA-wrapped nanoparticles
Peer-Reviewed Publication
Updates every hour. Last Updated: 16-Nov-2025 16:11 ET (16-Nov-2025 21:11 GMT/UTC)
CRISPR gene-editing machinery could transform medicine but is difficult to get into tissues and disease-relevant cells. New delivery system loads CRISPR machinery inside spherical nucleic acid (SNA) nanoparticles. Particles entered cells three times more effectively, tripled gene-editing efficiency, and decreased toxicity compared to current delivery methods.
Glaciers across High Mountain Asia are losing more than 22 gigatons of ice per year. The impact of a warming climate on glacial loss is undisputed—this new study provides the first evidence that seasonal shifts in rainfall and snowfall patterns, particularly of the South Asian monsoons, are also exacerbating glacier melting across the region.
A new UC Berkeley-led study provides fire-prone communities with actionable data on how wildfire mitigation strategies can reduce the destructiveness of wildfires by as much as 50%. In the study, the researchers used state-of-the-art wildfire simulation tools, combined with real-world data from five of the most destructive fires that occurred in California before 2022, to quantify the impact of home hardening and defensible space on wildfire risk.
MIT researchers designed molecules that can serve as the electrolyte in a lithium-ion battery and then quickly break apart at the end of the battery’s life, making it easier to recycle all of the components.