Cryo-electron microscopy visualization of a biological machine (VIDEO)

Memorial Sloan Kettering Cancer Center

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Cryo-EM helps researchers visualize biological machines in action. Here, a team led by structural biologist Richard Hite used the technology to help explain how certain channels regulate calcium signals in cells — a process important for the regulation of cell division and differentiation, cell metabolism, and cell death. Dysregulation of these channels, known as IP3Rs, is associated with diseases including cancer.

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Memorial Sloan Kettering Cancer Center

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