T-Cell Plasticity and Tumor Microenvironment Interactions (IMAGE)

Sichuan International Medical Exchange and Promotion Association

T-Cell Plasticity and Tumor Microenvironment Interactions

Caption

T cells dynamically adapt to signals in the TME, transitioning between effector, exhausted, and regulatory states. Cellular interactions, metabolic stress, and physical barriers (e.g., ECM) shape their functions, influencing cancer progression and treatment responses. Targeting these mechanisms could enhance immunotherapy efficacy.

Credit

The corresponding authors Dr. Yi-Zhou Jian and Dr. Han Wan

Usage Restrictions

Marked by the credited

License

Original content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.