Cryo-EM structure of full-length human NADK. (IMAGE)
Caption
(A) Tetrameric organization of human NADK. Four protomers are presented in different colors, and the N-terminal residues of each protomer are labeled. (B) Close-up view of NADK monomer. The N-terminal region (grey), N-terminal domain (NTD; green), C-terminal domain (CTD; cyan), connecting β strands 6 and 19 (magenta and orange), C-terminal α helix (blue), and three glycine-rich motifs (red) in a NADK monomer are color-coded, and secondary structural modules are labeled. (C, D) Two different views of NADK subdomains in the tetramer.
Credit
Genes & Diseases
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