Structural comparison of known and newly identified β-1,2-glucan-degrading enzymes (IMAGE)

Tokyo University of Science

Structural comparison of known and newly identified β-1,2-glucan-degrading enzymes

Caption

Enzymes in each group are superimposed with a GH144 enzyme. The GH144 enzyme and its substrate are shown in green and white, respectively. Group 1, Group 2, Group 3, TfSGL (GH162) and TiCGSTg(GH189) are shown in cyan, purple, light blue, orange, and pink, respectively. Residue numbers are of enzymes in each group (top) and the GH144 enzyme (bottom). Residues highlighted in red represent those that are indicators of SGL clan enzymes. Catalytic residues and candidates for catalytic residues are highlighted in bold letters. Asterisks represent diversity in the positions of (candidate) base catalysts or a nucleophile, which is also represented schematically in the next figure. 

Credit

Associate Professor Masahiro Nakajima from Tokyo University of Science, Japan

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