Hormonal response after eating (IMAGE)
Caption
Four primary hormones are released after eating: GLP-1 (blue), GIP (red), glucagon (violet) and PYY (green). Each hormone targets its own receptor. The effect of each receptor on the body are indicated using the same color code. The tetra-agonist compound designed by the Tufts team has components of each hormone and can activate each of the four same hormone receptors. The small grey circles on the tetra-agonist represent an attached lipid molecule that helps the tetra-agonist remain in the bloodstream longer by binding to albumin.
Credit
Tristan Dinsmore
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Image may only be used with stories reporting on the research of Krishna Kumar, Tufts University
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