PET scan tau cut-point video (VIDEO)

Keck School of Medicine of USC

Caption

The research team used the tau PET signal (PI-2620) to compare people with Alzheimer’s disease (AD) to healthy individuals. They found higher tau levels in memory-related brain areas, especially in the medial temporal lobe. This helped distinguish between healthy and AD groups. A threshold for tau positivity predicted cognitive problems well in Hispanic and non-Hispanic white participants, but was less accurate in non-Hispanic Black individuals.

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USC Stevens INI

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