Immunostaining for p-tau in the brains of PS19 mice injected with CIT or STZ and PBS or AMY. (IMAGE)
Caption
(A) Schematic representation of a sagittal mouse brain section from the Allen Brain Atlas. PS19 mice sections were stained with mAb AT8 (left panel) or mAb MC1 (right panel). (B) AT8 staining was quantified in the prefrontal cortex (PFC), hippocampus (H), and visual cortex (V. Cx). (B, E) STZ/AMY mice presented a larger AT8 and MC1+ stained area in the visual cortex in comparison with CIT/PBS and CIT/AMY (P < 0.05; n = 6 for all groups). (C, D) No differences were detected in the PFC (C), hippocampus (D), and other areas, such as the entorhinal cortex and amygdala
Credit
Genes & Diseases
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