WGD in Ovarian Cancer (IMAGE)

Memorial Sloan Kettering Cancer Center

WGD in Ovarian Cancer

Caption

MSK researchers found low levels of STING activation (orange) in ovarian cancers with high levels of whole-genome duplication (left) compared to those with low levels (right). This revealed how genome doubling can repress the STING pathway, which would normally activate immune cells to fight the cancer.

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Sohrab Shah Lab, Memorial Sloan Kettering Cancer Center

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