Reciprocal Metabolite Regulation in Shiraia-Associated Symbiosis (IMAGE)
Caption
A “donut” plate assay was established to assess the interactions between host Shiraia sp. S9 and the bacterial isolates from the fruiting body. Rhodococcus sp. No. 3 induced hypocrellin A (HA) biosynthesis in its fungal host through volatile-mediated elicitation, prompting Shiraia to leverage photoactivated extracellular HA for generating antibacterial reactive oxygen species that suppressed bacterial competitors. Rhodococcus countered this oxidative assault by synthesizing protective carotenoid antioxidants.
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Jian Wen Wang, College of Pharmaceutical Sciences, Soochow University, Suzhou, China
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