Liquid chromatography-mass spectrometry profiling of metabolomic reprogramming in CAL27 cells after ADAMTS9-AS2-Exos treatment and identification of metabolites. (IMAGE)
Caption
(A) The proportion of the identified metabolites in each chemical classification. Classification statistics are carried out based on the information of their chemical taxonomy. (B, C) The principal component analysis (PCA) score plots are shown separately in (B) positive and (C) negative ion modes. (D, E) The OPLS-DA score plots are shown in (D) positive and (E) negative ion modes. t[1] represents principal component 1, t[2] represents principal component 2, and the ellipse represents the 95% confidence interval. (F, G) The OPLS-DA permutation test plots are shown in (F) positive and (G) negative ion modes. (H, I) The volcano plots for metabolites after ADAMTS9-AS2-Exos treatment are shown in (H) positive and (I) negative ion modes. A9-AS2, ADAMTS9-AS2; Exos, exosomes; OPLS-DA, orthogonal partial least squares discriminant analysis.
Credit
Shanghui Zhou, Jingyu Zhan, Jia Wang, Jingang Yang, Dahe Zhang, Zhenming Li, Yue He
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CC BY-NC-ND