The mRNA expression levels of CISD1 in human pan-cancer. (IMAGE)
Caption
(A) CISD1 mRNA expression in various human normal tissues. Genotype Tissue Expression (GTEx) data for CISD1 mRNA in human normal tissues were downloaded from The Human Protein Atlas (THPA) and analyzed using GraphPad Prism. (B) CISD1 mRNA expression in various human cancer tissues. The Cancer Genome Atlas (TCGA) data for CISD1 mRNA expression across different cancer types were retrieved from THPA and analyzed using GraphPad Prism. (C) CISD1 mRNA expression levels in tumor tissues were compared with normal tissues across 33 cancer types. Differential expression analysis was conducted using GEPIA2, with a significance threshold of Q < 0.05 (Benjamini-Hochberg correction for multiple testing). Cancer types with significantly increased CISD1 expression are indicated in brown font, while those with significantly decreased expression are in blue font. N = normal tissue, and T = tumor tissue.
Credit
Caiyue Li, Zhipin Liang, Gabrielle Vontz, Connor Kent, Wenbo Ma, Lei Liu, Riya Dahal, Jovanny Zabaleta, Guoshuai Cai, Jia Zhou, Huangen Ding, Qiang Shen
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