Fig .2 (IMAGE)

The University of Osaka

Fig .2

Caption

(A) Cryogenic dual color super-resolution imaging of calcium ion distributions and actin filaments in neonatal rat cardiomyocytes and super-resolution three-dimensional view of calcium ion distribution

(B) Time-deterministic cryofixation of intracellular calcium ion wave propagation. UV laser stimulation initiates intracellular calcium ion wave propagation in the neonatal rat cardiomyocyte, followed by rapid freezing 120 ms after stimulation. The interval between event initiation and freezing is precisely determined with ±10 ms accuracy by electrically controlling the timing of both the light stimulation and cryogen injection.

Credit

2025, Kosuke Tsuji, Masahito Yamanaka et al., Time-deterministic cryo-optical microscopy, Light: Science & Applications

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Credit must be given to the creator.

License

CC BY

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