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Automated reaction platform and optical yield determination. a. platform overview. b., c., d., The robot explores a reaction space where two starting materials (A and B) combine to form product C, with outcomes varying depending on their concentrations and temperature. Using UV-Vis spectroscopy, the system records spectra of purified products at different concentrations. These reference patterns are then used to untangle the complex spectra from each reaction mixture, allowing the robot to precisely estimate product yields across thousands of conditions.
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Institute for Basic Science
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