figure2.png (IMAGE)

University of Washington

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Caption

The diagrams above show linker structures that can perform different logical operations. In box 1, the protein therapeutic (star) is released from a material (pink wedge) in the presence of either biomarker X or Y; in box 2, the protein will release only if both biomarkers X and Y are present. Linker structures can be connected in sequence or nested together to create more complex logical circuits. Future therapies could use these structures for highly targeted drug delivery.

Credit

DeForest et al./Nature Chemical Biology

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For use with appropriate credit.

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