Exercise mitigated a cafeteria diet–induced increase in immobility in the forced swim test and exerted a modest anxiolytic effect irrespective of diet. (IMAGE)
Caption
Exercise mitigated a cafeteria diet–induced increase in immobility in the forced swim test and exerted a modest anxiolytic effect irrespective of diet. (A) Experimental design. (B) Immobility: main effect of diet [F(1,43) = 10.41, p < 0.01] exercise [F(1,43) = 7.87, p < 0.01]; Swimming: main effects of diet [F(1,43) = 8.80, p < 0.001] and exercise [F(1,43) = 4.39, p < 0.05]; Climbing scores in the FST (n = 11–12). (C) Percentage of total time spent in EPM open arms (n = 11–12); effect of exercise [F(1,43) = 3.69, p = 0.062]; (D) Latency (s) to eat standard chow pellet in the NSF test arena (n = 11-12); Main effect of exercise [F(1,43) = 12.48, p < 0.001]; (E) Body weight–adjusted standard chow consumption (g) during NSF 30 min posttesting phase (n = 11–12); Main effect of diet [F(1,42) = 30.14, p < 0.0001], diet-exercise interaction [F(1,42) = 3.70, p = 0.061]; (F) Urine preference as time spent sniffing urine/total sniffing time in the FUST (n = 10–12). (G) Total distance travelled (m) in the OFT (n = 12). (H) Total time (s) spent in the center area of the OFT arena (n = 12). Data are expressed as mean ± SEM, p = 0.071, ∗p < 0.05 and ∗∗∗∗p < 0.0001 versus corresponding standard chow-fed group; p = 0.060, p = 0.058, p = 0.056 and #p < 0.05 versus corresponding sedentary group.
Credit
Yvonne Nolan
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CC BY