Applications of the learning and evaluation problems in protein family identification. (IMAGE)
Caption
(A) The learning problem and the Baum-Welch algorithm are used in constructing the hidden Markov model (HMM) of protein family A. After discovering the statistical characteristics of protein family A through multiple sequence alignment, the parameters were obtained with the help of the Baum-Welch algorithm to construct the HMM of protein family A. (B) The evaluation problem and forward algorithm are used in the identification of protein family A. A set of sequences is input into the HMM of protein family A, and each sequence is scored to determine whether it belongs to protein family A.
Credit
Yingnan Ma, Haiyan Chen, Jingxuan Kang, Xuying Guo, Chen Sun, Jing Xu, Junxian Tao, Siyu Wei, Yu Dong, Hongsheng Tian, Wenhua Lv, Zhe Jia, Shuo Bi, Zhenwei Shang, Chen Zhang, Hongchao Lv, Yongshuai Jiang, Mingming Zhang
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