Known risk factors for MASLD. (IMAGE)

First Hospital of Jilin University

Known risk factors for MASLD.

Caption

(A) Multiple environmental and genetic factors have been associated with MASLD. Most significant ones are highlighted here. (B) Several strong genetic risk factors for MASLD are highlighted here. ALT, alanine transaminase; GCKR, glucokinase regulator; GWAS, genome-wide association studies; HSD17B13, hydroxysteroid 17 beta-dehydrogenase 13; MASH, metabolic dysfunction-associated steatohepatitis; MASLD, metabolic dysfunction-associated steatotic liver disease; MBOAT7, membrane bound O-acyltransferase domain containing 7; PNPLA3, patatin-like phospholipase domain containing 3; T2DM, type 2 diabetes mellitus; TM6SF2, transmembrane 6 superfamily member 2; VLDL, very-low-density lipoprotein.

Credit

By Xiaocheng Charlie Dong et al.

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CC BY-NC

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