uPAR targeting (IMAGE)

Cold Spring Harbor Laboratory

uPAR targeting — Caption

Treating the intestinal linings with uPAR-targeting CAR T cells improved gut health in both young mice (left) and older animals (right). Treated intestines (shown in the second and fourth columns) exhibited reductions in uPAR cells (top row), as well as reductions in damaged senescent cells (middle row) and increases in healthy stem cells (bottom row).

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Amor Vegas & Beyaz labs/CSHL

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