Preventing a Transporter Protein from Doing its Job (VIDEO)
Caption
A Caltech-led team of biochemists has homed in on an underexplored small transporter called MurJ that is a vital part of the pathway bacteria use to build their chain-mail-like cell wall. The scientists have determined the common mechanism used by three different bacteria-killing viruses to block MurJ from doing its job.
Here, MurJ from E. coli transitions from an inward to an outward-facing state, where it is locked by a Sgl protein from one of these bacteria-killing viruses.
Credit
Yancheng Evelyn Li
Usage Restrictions
use credit
License
Original content