Fig. 2 (IMAGE)

The University of Osaka

Fig. 2

Caption

CTGF knockout in endothelial cells or pharmacological inhibition of integrin αV attenuates disease progression induced by hepatic congestion.

Credit

2026, Seiya Kato et al., Activation of the integrin αV–YAP–CTGF axis in liver sinusoidal endothelial cells promotes liver fibrogenesis, leading to portal hypertension and liver carcinogenesis in congestive hepatopathy, Gastroenterology

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