A new clue to how the body detects physical force (IMAGE)

Scripps Research Institute

A new clue to how the body detects physical force

Caption

A structural model of the force-sensing ion channel PIEZO2 (top), which is essential for the senses of touch and body position. Using a high-resolution imaging method called MINFLUX microscopy, scientists found that PIEZO2 is tethered to the cell’s internal scaffolding—the actin cytoskeleton—through a protein called filamin-B, helping fine-tune how the channel responds to force (bottom).

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Scripps Research

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