Protein sequence space for a biological function (IMAGE)

Okinawa Institute of Science and Technology (OIST) Graduate University

Protein sequence space for a biological function

Caption

An abstract, not-to-scale visual representation of different protein sequence spaces for a particular biological function. A large box represents all possible amino acid sequences (approximately 20L number of combinations, where L is the chain length). A smaller blue patch represents the sequences which create functional proteins, and an even smaller green area shows the sequences which we have historically confirmed to exist. Gold-colored lines show protein evolution pathways, with red paths describing evolutionary lines describing extinct pathways (i.e. those that aren’t thought to be present in modern biodiversity).

Credit

Isakova et al

Usage Restrictions

Credit must be given to the creator.

License

CC BY

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