In the DIO mouse model, ISM6200 demonstrated a good weight loss effect, mainly reducing fat while better retaining muscle mass. (IMAGE)
Caption
After 28 days of administration, compared with the control group, ISM6200 monotherapy achieved significant weight loss, with a relative weight reduction of 8.8% from the baseline. When ISM6200 was combined with Semaglutide, the weight loss effect was further enhanced, reaching 23.8% within the same administration period, while the DIO control group gained 2.4% in weight. The above data provided strong support for subsequent clinical development.
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Insilico Medicine
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