Nucleosome movements in the nucleus (VIDEO)

Research Organization of Information and Systems

Caption

(Left) Video of linker histone H1 in the nuclei of human living cells observed by super-resolution microscopy. (Right) Molecular dynamics simulation reproducing interactions between nucleosomes and linker histone H1. Red, DNA; yellow, histones; blue, linker histone H1. H1 moves dynamically while bridging multiple nucleosomes.

Credit

Masa A. Shimazoe, Jan Huertas,Charles Phillips, Rosana Collepardo-Guevara & Kazuhiro Maeshima, National Institute of Genetics, ROIS and University of Cambridge

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