Spatial transcriptomic analyses of tumor samples from control and NT-I7-treated mice. (IMAGE)

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Spatial transcriptomic analyses of tumor samples from control and NT-I7-treated mice.

Caption

(A, B) H&E images (A) and spatial representation of tumor regions (B) in control and NT-I7-treated tumor samples. (C, E, F) Spatial localization of unsupervised clusters. (D) UMAP of unsupervised clusters from control and NT-I7-treated samples. (G) Volcano plot of differentially expressed genes. (H) Heatmap of selected immune-related gene transcripts. Alv. macro., alveolar macrophages; ATP, alveolar type pneumocytes.

Credit

Trang Dinh, Judong Lee, Sidra Islam, Namita Nanda, Dijana Bjelivuk, Dathan Andrews, Jiasen Zhang, Nikita L. Mani, Jin Zhou, Alexandra A. Wolfarth, Donghoon Choi, Rafi Ahmed, Joseph Skitzki, Deyu Fang, Weihong Guo, Zhenghe Wang, Rebecca C. Obeng

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