Role of intratumour TERT expression. (IMAGE)
Caption
(A) OS by TERT expression. (B) Main gene sets regulated under differential TERT expression. (C) Enrichment map of gene sets significantly correlated with TERT expression within the tumour microenvironment of iCCA. Node size represents the size of each gene set and connecting lines (edges) indicate the similarity of gene sets. ECM, extracellular matrix; iCCA, intrahepatic cholangiocarcinoma; JNK, c-Jun N-terminal kinase; OS, overall survival; TERT, telomerase reverse transcriptase; TGF, transforming growth factor; Treg, regulatory T cell; VEGF, vascular endothelial growth factor.
Credit
By Isabella Lurje, Justus Pein, Paul Horn, et al.
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License
CC BY